Mrgpre^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Mrgpre^tm1Dgen
• Name: MAS-related GPR, member E; targeted mutation 1, Deltagen
• MGI ID: MGI:5646195
• Synonyms: MrgE KO
• Gene: Mrgpre Location: Chr7:143332100-143338237 bp, - strand Genetic Position: Chr7, 88.31 cM
• Alliance: Mrgpre^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222382
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 776 base pairs from within the 930 base pair coding region located in exon 2 were deleted and replaced with a 7,076 base pair IRES-lacZ reporter and neomycin resistance cassette. No transcripts from this gene were detected in all homozygous tissues tested. (J:222382)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrgpre Mutation: 19 strains or lines available

References

• Original: J:222382 Cox PJ, et al., The effect of deletion of the orphan G - protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice. Mol Pain. 2008;4:2
• All: 1 reference(s)