Gt(ROSA)26Sor^{tm2(CAG-Lancl1)Pfw}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-Lancl1)Pfw}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Paul Worley
• MGI ID: MGI:5646274
• Synonyms: Rosa26-LanCL1-V5
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-Lancl1)Pfw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214805
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(CAG-Lancl1)Pfw} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Lancl1

• Mutation details: A CAG promoter, floxed stop cassette and a V5 tagged Lancl1 cDNA were inserted in the locus via homologous recombination. (J:214805)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:214805 Huang C, et al., Developmental and activity-dependent expression of LanCL1 confers antioxidant activity required for neuronal survival. Dev Cell. 2014 Aug 25;30(4):479-87
• All: 2 reference(s)