Ica1l^b2b3465Clo
Chemically induced Allele Detail

Summary

• Symbol: Ica1l^b2b3465Clo
• Name: islet cell autoantigen 1-like; Bench to Bassinet Program (B2B/CVDC), mutation 3465 Cecilia Lo
• MGI ID: MGI:5648234
• Gene: Ica1l Location: Chr1:60024955-60082646 bp, - strand Genetic Position: Chr1, 30.45 cM, cytoband C2
• Alliance: Ica1l^b2b3465Clo page

Mutant 3465-007-1 (E17.5) exhibits abnormal arrangement of the great arteries which was diagnosed by episcopic confocal microscopy as ventricular non-compaction.

Show the 21 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a A-to-T substitution at position 60085088 after nucleotide 18 (c.18A>T). The mutant phenotype is attributed to a mutation in the Ica1l gene. (J:175213)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ica1l Mutation: 23 strains or lines available

Notes

Summative Diagnosis:
Female 3465-007 is harvested according to Echo findings: 2A2C0D6T, e17.5 , two mutants were suspected. Penetration is bad. One is PTA, one is DORV.(XL)

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)