Mirc32^tm1Jtm
Targeted Allele Detail

Summary

• Symbol: Mirc32^tm1Jtm
• Name: microRNA cluster 32, including Mir143 and Mir145a; targeted mutation 1, Joshua T Mendell
• MGI ID: MGI:5648481
• Synonyms: miR-143/145^Neo
• Gene: Mirc32 Location: Chr18:61780896-61782329 bp Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214382
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of Mir143 and an FRT flanked neo cassette and loxP site were inserted downstream of Mir145a via homologous recombination. (J:214382)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc32 Mutation: 3 strains or lines available

References

• Original: J:214382 Chivukula RR, et al., An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 2014 May 22;157(5):1104-16
• All: 1 reference(s)