Clec16a^tm1.1Hhak
Targeted Allele Detail

Summary

• Symbol: Clec16a^tm1.1Hhak
• Name: C-type lectin domain family 16, member A; targeted mutation 1.1, Hakon Hakonarson
• MGI ID: MGI:5648633
• Synonyms: Clec16a^loxP
• Gene: Clec16a Location: Chr16:10363203-10562742 bp, + strand Genetic Position: Chr16, 5.68 cM
• Alliance: Clec16a^tm1.1Hhak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214528
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 was floxed and an FRT flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:214528)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec16a Mutation: 48 strains or lines available

References

• Original: J:214528 Soleimanpour SA, et al., The diabetes susceptibility gene Clec16a regulates mitophagy. Cell. 2014 Jun 19;157(7):1577-90
• All: 9 reference(s)