Stra6^tm1Jvli
Targeted Allele Detail

Summary

• Symbol: Stra6^tm1Jvli
• Name: stimulated by retinoic acid gene 6; targeted mutation 1, Johannes Von Lintig
• MGI ID: MGI:5648726
• Synonyms: Stra6^neo
• Gene: Stra6 Location: Chr9:57971071-58061279 bp, + strand Genetic Position: Chr9, 31.63 cM, cytoband C
• Alliance: Stra6^tm1Jvli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214659
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 603 bp DNA fragment including all of exon 2 was replaced with a floxed neo cassette via homologous recombination. (J:214659)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stra6 Mutation: 50 strains or lines available

References

• Original: J:214659 Amengual J, et al., STRA6 is critical for cellular vitamin A uptake and homeostasis. Hum Mol Genet. 2014 Oct 15;23(20):5402-17
• All: 1 reference(s)