Ephb1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ephb1^tm1Dgen
• Name: Eph receptor B1; targeted mutation 1, Deltagen
• MGI ID: MGI:5659739
• Synonyms: Ephb1^-
• Gene: Ephb1 Location: Chr9:101799327-102231892 bp, - strand Genetic Position: Chr9, 54.15 cM
• Alliance: Ephb1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214959
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A Lac0-SA-IRES-lacZ-neo/kan cassette was inserted replacing 100 bp of genomic sequence in exon 8 via homologous recombination. Western blot analysis confirmed the absence of protein in brain lysates from P1 homozygous mutant mice. (J:214959)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ephb1 Mutation: 43 strains or lines available

References

• Original: J:214959 Lodato S, et al., Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug;17(8):1046-54
• All: 1 reference(s)