Nepro^tm1.1Tets
Targeted Allele Detail

Summary

• Symbol: Nepro^tm1.1Tets
• Name: nucleolus and neural progenitor protein; targeted mutation 1.1, Tetsuichiro Saito
• MGI ID: MGI:5659990
• Synonyms: Nepro^Venus
• Gene: Nepro Location: Chr16:44544664-44557647 bp, + strand Genetic Position: Chr16, 29.04 cM
• Alliance: Nepro^tm1.1Tets page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223645
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a Venus and floxed neomycin resistance cassette with a polyadenylation sequence immediately downstream of the translation initiation site. Cre-mediated recombination removed the selection cassette. (J:223645)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nepro Mutation: 32 strains or lines available

References

• Original: J:223645 Hashimoto M, et al., Nepro is localized in the nucleolus and essential for preimplantation development in mice. Dev Growth Differ. 2015 Sep;57(7):529-38
• All: 1 reference(s)