Cdk5r1^tm2Ohsh
Targeted Allele Detail

Summary

• Symbol: Cdk5r1^tm2Ohsh
• Name: cyclin dependent kinase 5, regulatory subunit 1; targeted mutation 2, Toshio Ohshima
• MGI ID: MGI:5660032
• Synonyms: p35^flox
• Gene: Cdk5r1 Location: Chr11:80367849-80372010 bp, + strand Genetic Position: Chr11, 47.94 cM
• Alliance: Cdk5r1^tm2Ohsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215344
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted 3' of the coding region and a loxP site was inserted 5' of the coding region via homologous recombination. (J:215344)

Expression

In Mice Carrying this Mutation:

74 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk5r1 Mutation: 13 strains or lines available

References

• Original: J:215344 He X, et al., Cdk5/p35 is required for motor coordination and cerebellar plasticity. J Neurochem. 2014 Oct;131(1):53-64
• All: 5 reference(s)