Tg(Myh6-Jup)2Ajm
Transgene Detail

Summary

• Symbol: Tg(Myh6-Jup)2Ajm
• Name: transgene insertion 2, Ali J Marian
• MGI ID: MGI:5660502
• Synonyms: PG^WT
• Transgene: Tg(Myh6-Jup)2Ajm Location: unknown
• Alliance: Tg(Myh6-Jup)2Ajm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Jup)2Ajm expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Jup (MGI:96650)

• Mutation details: The murine plakoglobin gene is under the control of the the cardiac-restricted alpha-myosin heavy chain promoter. Three sequential Flag epitopes were placed at the N-terminal domain. Two lines were generated: 1 and 2. Line 2 is the higher expressing line (J:192719)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:192719 Lombardi R, et al., Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2011 Dec 9;109(12):1342-53
• All: 1 reference(s)