Ints10tm1b(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Ints10tm1b(KOMP)Wtsi |
Name: |
integrator complex subunit 10; targeted mutation 1b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5661967 |
Gene: |
Ints10 Location: Chr8:69245729-69282062 bp, + strand Genetic Position: Chr8, 33.88 cM, cytoband C1
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Alliance: |
Ints10tm1b(KOMP)Wtsi page
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IMPC: |
Ints10 gene page |
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Mutant Cell Line: |
EPD0044_1_B02 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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Parent Cell Line: |
JM8.F6 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_gt0
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Mutation details: The L1L2_gt0 cassette was inserted at position 69254500 of Chromosome 8 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site was inserted downstream of the targeted exon(s) at position 69255926. The critical exon(s) were thus flanked by loxP sites and subsequent Cre-mediated excision deleted the critical sequence and neomycin selection cassette yielding this knockout reporter allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:148605, J:173534, J:188991)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
5 reference(s) |
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