Noc2l^tm1.2Arte
Targeted Allele Detail

Summary

• Symbol: Noc2l^tm1.2Arte
• Name: NOC2 like nucleolar associated transcriptional repressor; targeted mutation 1.2, TaconicArtemis
• MGI ID: MGI:5662106
• Gene: Noc2l Location: Chr4:156320376-156332073 bp, + strand Genetic Position: Chr4, Syntenic
• Alliance: Noc2l^tm1.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216490
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3 and a loxP site and FRT flanked puro cassette were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the puro cassette. Cre mediated recombination removed exons 3 and 4. (J:216490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Noc2l Mutation: 19 strains or lines available

References

• Original: J:216490 Ma CA, et al., Novel INHAT repressor (NIR) is required for early lymphocyte development. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13930-5
• All: 1 reference(s)