Grm7^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Grm7^m1Btlr
• Name: glutamate receptor, metabotropic 7; mutation 1, Bruce Beutler
• MGI ID: MGI:5688492
• Synonyms: shaky
• Gene: Grm7 Location: Chr6:110622542-111544191 bp, + strand Genetic Position: Chr6, 51.19 cM
• Alliance: Grm7^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T transversion at base pair 111,495,791 (v38) on chromosome 6, or base pair 850,334 in the GenBank genomic region NC_000072. The mutation corresponds to residue 2,860 in the NM_177328 mRNA sequence in exon 9 of 10 total exons and residue 2,877 in the ENSMUST00000071076 cDNA sequence in exon 9 of 11 total exons. The mutation results in substitution of lysine 864 (K864) for a premature stop codon (K864*) in all isoforms. (J:224658)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grm7 Mutation: 125 strains or lines available

References

• Original: J:224658 SoRelle J, et al., Mutagenetix entry for shaky. MGI Direct Data Submission. 2015
• All: 1 reference(s)