Fasl^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fasl^m2Btlr
• Name: Fas ligand; mutation 2, Bruce Beutler
• MGI ID: MGI:5688496
• Synonyms: riogrande2
• Gene: Fasl Location: Chr1:161608260-161616064 bp, - strand Genetic Position: Chr1, 69.95 cM
• Alliance: Fasl^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to C transversion at base pair 161,787,138 (v38) on chromosome 1, or base pair 8,401 in the GenBank genomic region NC_000067. The mutation corresponds to residue 565 in the mRNA sequence NM_010177 within exon 2 of 4 total exons. The mutation results in a serine (S) to arginine (R) substitution at position 119 (S119R) in the protein. (J:224659)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fasl Mutation: 37 strains or lines available

References

• Original: J:224659 Wang KW, et al., Mutagenetix entry for riogrande2. MGI Direct Data Submission. 2015
• All: 1 reference(s)