Cd22^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd22^m4Btlr
• Name: CD22 antigen; mutation 4, Bruce Beutler
• MGI ID: MGI:5688497
• Synonyms: gansu
• Gene: Cd22 Location: Chr7:30564829-30579767 bp, - strand Genetic Position: Chr7, 19.26 cM
• Alliance: Cd22^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A transition at base pair 30,870,105 (v38) on chromosome 7, or base pair 10,238 in the GenBank genomic region NC_000073. The mutation corresponds to residue 1,948 in the mRNA sequence NM_001043317 (variant 1) within exon 10 of 16 total exons and to residue 1,823 in the mRNA sequence NM_009845 (variant 2) within exon 8 of 14 total exons. The mutated nucleotide is indicated in red. The mutation results in a valine (V) to methionine (M) substitution at position 529 (V529M) in both isoforms. (J:224660)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd22 Mutation: 64 strains or lines available

References

• Original: J:224660 Zeng M, et al., Mutagenetix entry for gansu. MGI Direct Data Submission. 2015
• All: 1 reference(s)