Rbm38^tm1.1Xch
Targeted Allele Detail

Summary

• Symbol: Rbm38^tm1.1Xch
• Name: RNA binding motif protein 38; targeted mutation 1.1, Xinbin Chen
• MGI ID: MGI:5688508
• Gene: Rbm38 Location: Chr2:172863722-172876527 bp, + strand Genetic Position: Chr2, 95.67 cM
• Alliance: Rbm38^tm1.1Xch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174192
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a pgk-neo cassette and loxP site were inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1 and the neo cassette. (J:174192)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Rbm38^tm1.1Xch

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm38 Mutation: 9 strains or lines available

References

• Original: J:174192 Zhang J, et al., Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas. Genes Dev. 2011 Jul 15;25(14):1528-43
• All: 6 reference(s)