Tg(CAG-cat,-Il18)#Thos
Transgene Detail

Summary

• Symbol: Tg(CAG-cat,-Il18)#Thos
• Name: transgene insertion, Tomoaki Hoshino
• MGI ID: MGI:5688534
• Synonyms: CAG-loxP-CAT-loxp-IL-18
• Transgene: Tg(CAG-cat,-Il18)#Thos Location: unknown
• Alliance: Tg(CAG-cat,-Il18)#Thos page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-cat,-Il18)#Thos expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il18 (MGI:107936)

• Mutation details: This transgene consists of the cytomegalovirsus/chicken beta-actin (CAG) promoter, loxP flanked chloramphenicol acetyltransferase (cat) gene, and mouse mature Il18.Cre mediated recombination to remove the floxed cat results in expression of the mouse cDNA.Three lines were established, however the pound symbol (#) is used because the line is not specified and/or lines are pooled. (J:147547)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:147547 Hoshino T, et al., Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13. Am J Respir Crit Care Med. 2007 Jul 1;176(1):49-62
• All: 1 reference(s)