Mlph^ln-2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mlph^ln-2Btlr
• Name: melanophilin; leaden 2 Bruce Beutler
• MGI ID: MGI:5688600
• Synonyms: beau
• Gene: Mlph Location: Chr1:90842807-90878864 bp, + strand Genetic Position: Chr1, 45.73 cM
• Alliance: Mlph^ln-2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transition at base pair 90,928,122 (v38) on chromosome 1, or base pair 13,101 in the GenBank genomic region NC_000067. The mutation corresponds to residue 428 in the mRNA sequence NM_053015 within exon 3 of 16 total exons. The mutation results in a cysteine (C) to arginine (R) substitution at position 84 (C84R) in the protein. (J:224669)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlph Mutation: 38 strains or lines available

References

• Original: J:224669 Daniel C, et al., Mutagenetix entry for beau. MGI Direct Data Submission. 2015
• All: 1 reference(s)