Rxfp3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Rxfp3^tm1Dgen
• Name: relaxin family peptide receptor 3; targeted mutation 1, Deltagen
• MGI ID: MGI:5688755
• Gene: Rxfp3 Location: Chr15:11033803-11038054 bp, - strand Genetic Position: Chr15, 5.42 cM
• Alliance: Rxfp3^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216975
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The bases comprising the first transmembrane domain were replaced with a lacZ-neo cassette via homologous recombination. (J:216975)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rxfp3 Mutation: 22 strains or lines available

References

• Original: J:216975 Hosken IT, et al., Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal. Behav Brain Res. 2014 Sep 22;278C:167-175
• All: 3 reference(s)