Neto1^{tm1.1(cre)Jrs}
Targeted Allele Detail

Summary

• Symbol: Neto1^{tm1.1(cre)Jrs}
• Name: neuropilin (NRP) and tolloid (TLL)-like 1; targeted mutation 1.1, Joshua R Sanes
• MGI ID: MGI:5688860
• Synonyms: Neto1^Cre
• Gene: Neto1 Location: Chr18:86413077-86524843 bp, + strand Genetic Position: Chr18, 58.47 cM
• Alliance: Neto1^{tm1.1(cre)Jrs} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214586
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Neto1^{tm1.1(cre)Jrs} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Neto1 (MGI:2180216)

• Mutation details: A cre recombinase gene with a polyadenylation sequence and an FRT-flanked neomycin resistance cassette was targeted to exon 1. Flp-mediated recombination removed the selection cassette. (J:214586)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Neto1 (mouse) Summary of all recombinase alleles driven by Neto1. Comparative matrix view of recombinase activities Alliance mouse Neto1 gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Neto1 Mutation: 42 strains or lines available

References

• Original: J:214586 Duan X, et al., Type II cadherins guide assembly of a direction-selective retinal circuit. Cell. 2014 Aug 14;158(4):793-807
• All: 3 reference(s)