Kcng4^{tm1.1(cre)Jrs}
Targeted Allele Detail

Summary

• Symbol: Kcng4^{tm1.1(cre)Jrs}
• Name: potassium voltage-gated channel, subfamily G, member 4; targeted mutation 1.1, Joshua R Sanes
• MGI ID: MGI:5688863
• Synonyms: Kcng4^Cre
• Gene: Kcng4 Location: Chr8:120350593-120362419 bp, - strand Genetic Position: Chr8, 68.07 cM
• Alliance: Kcng4^{tm1.1(cre)Jrs} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214586
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Kcng4^{tm1.1(cre)Jrs} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Kcng4 (MGI:1913983)

• Mutation details: A cre recombinase gene with a polyadenylation sequence and an FRT-flanked neomycin resistance cassette was targeted to exon 2. Flp-mediated recombination removed the selection cassette. (J:214586)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kcng4 (mouse) Summary of all recombinase alleles driven by Kcng4. Comparative matrix view of recombinase activities Alliance mouse Kcng4 gene page

Expression

In Mice Carrying this Mutation:

6 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcng4 Mutation: 24 strains or lines available

References

• Original: J:214586 Duan X, et al., Type II cadherins guide assembly of a direction-selective retinal circuit. Cell. 2014 Aug 14;158(4):793-807
• All: 27 reference(s)