Lbn21^SM/J
QTL Variant Detail

Summary

• QTL variant: Lbn21^SM/J
• Name: long bones 21; SM/J
• MGI ID: MGI:5689487
• QTL: Lbn21 Location: unknown Genetic Position: Chr4, Syntenic

Variant origin

• Strain of Specimen: SM/J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:150240

QTLs for long bone length were mapped in F2 and F3 generations of an intercross of

LG/J and SM/J mice. LG/J mice were selected for large body size (~40 g) at 60 days and SM/J mice were selected for small body size (~20 g) at 60 days. There were 506 F2 Mice and 1605 F3 mice.

. The following results were obtained :next to the Marker and Chr in parenthesis are recorded the, cM location, Mbp location ,and nearest SNP

Chr1

Lbn1c (Chr 1,19 cM,41.03 Mbp ,rs13475,837)

Lbn1(Chr 1, 19 cM, 89.08 Mbp, petM22381-169-2)

Lbn18 (Chr1, 56 cM, 152.21 Mbp, rs3688042).

Chr 2

Lbn2a (45 cM, 77.35 Mbp, rs3713848)

Lbn2 (76cM, 156.29 Mbp, gnf02.161.674)

Chr3

Lbn3a (29cM, 60.39 Mbp, rs13477154)

Lbn19 (60cM, 115.92 Mbp,rs13477364)

Lbn20 (81cM, 145.80 Mbp,rs3722447)

Chr4

Lbn11 (29cM, 63.67 Mbp, gnf04.062.327)

Lbn21 (64cM, 133.39 Mbp, rs13477996)

Chr5

Lbn22 (64cM, 128.12 Mbp, rs6377710)

Chr 6:

Lbn23(37 cM 85.33 Mbp, rs13478882)

Lbn5c (72 cM, 144.01 Mbp rs6199136)

Cht7:

Lbn6a (25 cM 50.Mbp, gnf07.056.997)

Chr8:

Lbn7b (2 cM, 9..80, Mbp, rs6273176)

Lbn7a (39 cM 71.85, Mbp, rs13479811)

Chr9:

Lbn24(13.5 cM , 29.85 Mbp, CEL-9_29909656)

Lbn25(42.4 cM 73.42 Mbp rs13480273)

Lbn8c(74 cM 119.74 Mbp, rs8254378)

Chr 10

Lbn9a(33 cM 82.11 Mbp , rs13480678)

Lbn9b(66 cM127.64 Mbp, rs6290842)

Chr 11:

Lbn26 (7 cM16.57 Mbp, rs3724116)

Chr 13:

Lbn14 (48 cM 98.97 Mbp, rs13481990)

Chr14

Lbn27 (43cM 93.07 Mbp, rs3718262)

Chr15:

Lbn28 (25 cM 60.88 Mbp, rs4139476)

Lbn29( 43cM, 87.73 Mbp, rs3720931)

Chr 17:

Lbn10a(17 cM, 41.06 Mbp, CEL-17_40073719)

Chr 19

Lbn17 (4 cM 10.79 Mbp, rs6307076)

References

• Original: J:150240 Norgard EA, et al., Identification of quantitative trait loci affecting murine long bone length in a two-generation intercross of LG/J and SM/J Mice. J Bone Miner Res. 2008 Jun;23(6):887-95
• All: 1 reference(s)