Meis1^tm2.1Mtor
Targeted Allele Detail

Summary

• Symbol: Meis1^tm2.1Mtor
• Name: Meis homeobox 1; targeted mutation 2.1, Miguel Torres
• MGI ID: MGI:5689566
• Synonyms: Meis1^ECFP
• Gene: Meis1 Location: Chr11:18830428-18968992 bp, - strand Genetic Position: Chr11, 11.11 cM
• Alliance: Meis1^tm2.1Mtor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217599
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The last 6 nucleotides from exon 1 and the first 51 nucleotides from intron 1 were replaced with ECFP, polyadenylation sequence and self-excising neomycin resistance cassette. The final allele lacks the selection cassette. (J:217599)

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meis1 Mutation: 46 strains or lines available

References

• Original: J:217599 Gonzalez-Lazaro M, et al., Two new targeted alleles for the comprehensive analysis of Meis1 functions in the mouse. Genesis. 2014 Dec;52(12):967-75
• All: 3 reference(s)