Tg(Aplnr-cre/ERT2)#Krh
Transgene Detail

Summary

• Symbol: Tg(Aplnr-cre/ERT2)#Krh
• Name: transgene insertion, Kristy Red-Horse
• MGI ID: MGI:5689869
• Synonyms: Apj-CreER, ApjCreER
• Transgene: Tg(Aplnr-cre/ERT2)#Krh Location: unknown
• Alliance: Tg(Aplnr-cre/ERT2)#Krh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Aplnr-cre/ERT2)#Krh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aplnr (MGI:1346086)

• Mutation details: The transgene contains BAC RP24-301A16 into which an inducible cre recombinase gene (cre/ERT2) was introduced at the start site to achieve expression in the sinus venosus. Two lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:217615)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aplnr (mouse) Summary of all recombinase alleles driven by Aplnr. Comparative matrix view of recombinase activities Alliance mouse Aplnr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Transgene expression is not detected in the endocardium or epicardium.

References

• Original: J:217615 Chen HI, et al., VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914
• All: 15 reference(s)