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Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr
Transgene Detail
Summary
Symbol: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr
Name: transgene insertion, Bruce Beutler
MGI ID: MGI:5689887
Synonyms: Gt(ROSA)26Sorem1(Kdelr1)Btlr, Tg(Kdelr1)
Transgene: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr  Location: unknown  
Alliance: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse promoter drives ubiquitous expression of the mouse sequence. 5 founders were identified. The pound symbol (#0 is used when no line is specified and/or lines are pooled. (J:224970)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Originally created using fertilized Kdelr1dgy oocytes.
References
Original:  J:224970 Siggs OM, et al., Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5706-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory