Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr
Transgene Detail

Summary

• Symbol: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr
• Name: transgene insertion, Bruce Beutler
• MGI ID: MGI:5689887
• Synonyms: Gt(ROSA)26Sor^{em1(Kdelr1)Btlr}, Tg(Kdelr1)
• Transgene: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr Location: unknown
• Alliance: Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The mouse promoter drives ubiquitous expression of the mouse sequence. 5 founders were identified. The pound symbol (#0 is used when no line is specified and/or lines are pooled. (J:224970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Originally created using fertilized Kdelr1^dgy oocytes.

References

• Original: J:224970 Siggs OM, et al., Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5706-14
• All: 1 reference(s)