Tg(Tbx21-ZsGreen,-cre/ERT2)H3Jfz
Transgene Detail

Summary

• Symbol: Tg(Tbx21-ZsGreen,-cre/ERT2)H3Jfz
• Name: transgene insertion H3, Jinfang Zhu
• MGI ID: MGI:5690125
• Synonyms: B6-T-betZsGreen-T2ACreERT2-H3, T-bet-ZsGreen-T2A-CreER^T2
• Transgene: Tg(Tbx21-ZsGreen,-cre/ERT2)H3Jfz Location: unknown
• Alliance: Tg(Tbx21-ZsGreen,-cre/ERT2)H3Jfz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Tbx21-ZsGreen,-cre/ERT2)H3Jfz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tbx21 (MGI:1888984)

• Mutation details: The transgene contains BAC RP23-237M14 with a ZsGreen reporter gene, T2A peptide, and inducible cre recombinase gene (cre/ERT2) introduced at the translation initiation site. Four founders were generated. Line H3 contains 1 copy of the transgene. (J:223248)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx21 (mouse) Summary of all recombinase alleles driven by Tbx21. Alliance mouse Tbx21 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:223248 Yu F, et al., Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance. Nat Immunol. 2015 Feb;16(2):197-206
• All: 4 reference(s)