Fgf17^{tm1(cre/ERT2)Jlr}
Targeted Allele Detail

Summary

• Symbol: Fgf17^{tm1(cre/ERT2)Jlr}
• Name: fibroblast growth factor 17; targeted mutation 1, John L R Rubenstein
• MGI ID: MGI:5690227
• Synonyms: Fgf17^CreER
• Gene: Fgf17 Location: Chr14:70873643-70879708 bp, - strand Genetic Position: Chr14, 36.4 cM
• Alliance: Fgf17^{tm1(cre/ERT2)Jlr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222259
• Parent Cell Line: PRX-B6T (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Fgf17^{tm1(cre/ERT2)Jlr} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fgf17 (MGI:1202401)

• Mutation details: An inducible cre recombinase gene (cre/ERT2), polyadenylation sequence and floxed neomycin resistance cassette replace the coding sequence in exon 1, intron 1 and exon 2. (J:222259)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fgf17 (mouse) Summary of all recombinase alleles driven by Fgf17. Alliance mouse Fgf17 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf17 Mutation: 35 strains or lines available

References

• Original: J:222259 Hoch RV, et al., Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center. Neural Dev. 2015;10:8
• All: 1 reference(s)