Rtn3^tm1Yanr
Targeted Allele Detail

Summary

• Symbol: Rtn3^tm1Yanr
• Name: reticulon 3; targeted mutation 1, Riqiang Yan
• MGI ID: MGI:5691761
• Gene: Rtn3 Location: Chr19:7403266-7460646 bp, - strand Genetic Position: Chr19, 5.32 cM, cytoband A
• Alliance: Rtn3^tm1Yanr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217161
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP-flanked neomycin selection cassette replaced a genomic fragment containing exons 4-9. (J:217161)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn3 Mutation: 52 strains or lines available

References

• Original: J:217161 Shi Q, et al., Impact of RTN3 deficiency on expression of BACE1 and amyloid deposition. J Neurosci. 2014 Oct 15;34(42):13954-62
• All: 6 reference(s)