Tsn^tm1Jmat
Targeted Allele Detail

Summary

• Symbol: Tsn^tm1Jmat
• Name: translin; targeted mutation 1, Junichiro Matsuda
• MGI ID: MGI:5691814
• Synonyms: Translin^-
• Gene: Tsn Location: Chr1:118226244-118239463 bp, - strand Genetic Position: Chr1, 52.14 cM
• Alliance: Tsn^tm1Jmat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222381
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 10.5 kb genomic fragment containing the coding exons of the gene was deleted and replaced with a neomycin selection cassette. Western blot using protein samples derived from testes of homozyous mice showed that no detectable protein is expressed. (J:222381)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsn Mutation: 27 strains or lines available

References

• Original: J:222381 Fukuda Y, et al., Contribution of Translin to hematopoietic regeneration after sublethal ionizing irradiation. Biol Pharm Bull. 2008 Feb;31(2):207-11
• All: 5 reference(s)