Nr3c2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nr3c2^m1Btlr
• Name: nuclear receptor subfamily 3, group C, member 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5691956
• Synonyms: naughty
• Gene: Nr3c2 Location: Chr8:77626422-77971641 bp, + strand Genetic Position: Chr8, 36.34 cM
• Alliance: Nr3c2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G transition at base pair 76,908,668 (v38) on chromosome 8, or base pair 9,408 in the GenBank genomic region NC_000074, corresponding to residue 432 in the NM_001083906 mRNA sequence in exon 2 of 9 total exons. The mutation results in an isoleucine (I) to valine (V) substitution at position 133 (I133V) in the encoded protein. (J:225269)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr3c2 Mutation: 53 strains or lines available

References

• Original: J:225269 Chen Z, et al., Mutagenetix entry for naughty. MGI Direct Data Submission. 2015
• All: 1 reference(s)