Summary |
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Variant origin |
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Variant description |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:151141Febrile seizures susceptibility (FS) and febrile seizure latency (FSL) were determined in both sexes of the host strain(C57BL/6J), the donor strain (A/J) and mouse chromosome substitutionstrains (CSS) to identify novel FS susceptibility quantitativetrait loci. C57BL/6J mice were more susceptible to FS than A/J mice.Strains CSS 1, CSS 2, CSS 6, CSS 10, CSS 13 and CSS X representing Chrs 1, 2, 6, 10 ,13 and X respectively were identified as significantly different from strain (C57BL/6J; P <0.003) and thus are presumed by the authors to contain 1 or more loci that affect FS in mice. These QTLs are symbolized as Fss1(chr1), Fss2(chr2), Fss3(chr6), Fss4(chr10) and Fss5(Chr 13) and Fss6(Chr X). |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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