Eef1a1^tm1Tcrl
Targeted Allele Detail

Summary

• Symbol: Eef1a1^tm1Tcrl
• Name: eukaryotic translation elongation factor 1 alpha 1; targeted mutation 1, Thomas Carroll
• MGI ID: MGI:5692071
• Synonyms: EF1a^Crb3-GFP
• Gene: Eef1a1 Location: Chr9:78385735-78389006 bp, - strand Genetic Position: Chr9, 43.65 cM, cytoband E1
• Alliance: Eef1a1^tm1Tcrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225273
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The construct is designed with a loxP-flanked neomycin resistance (neo) cassette followed by a crumbs family member 3 (crumbs3)-green fluorescent protein (GFP) fusion protein. The floxed-neo acts as a transcriptional STOP cassette. The construct was targeted to exon 1 of the gene. (J:225273)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eef1a1 Mutation: 60 strains or lines available

References

• Original: J:225273 Pan X, et al., A Cre-inducible fluorescent reporter for observing apical membrane dynamics. Genesis. 2015 Mar-Apr;53(3-4):285-93
• All: 2 reference(s)