Prkra^lear-5J
Spontaneous Allele Detail

Summary

• Symbol: Prkra^lear-5J
• Name: protein kinase, interferon inducible double stranded RNA dependent activator; little ears 5 Jackson
• MGI ID: MGI:5692073
• Gene: Prkra Location: Chr2:76460242-76478359 bp, - strand Genetic Position: Chr2, 45.07 cM
• Alliance: Prkra^lear-5J page

Mutation origin

• Strain of Origin: BTBR T⁺ Itpr3^tf/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This spontaneous T insertion/duplication (an extra T in the poly(T) stretch) between chromosome 2 76,636,870-76 bp (GRCm38) causes a frameshift that introduces 7 novel amino acids followed by a premature stop codon. (J:223062)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkra Mutation: 24 strains or lines available

References

• Original: J:223062 Palmer K, et al., Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology. Dev Biol. 2016 Jul 15;415(2):216-27
• All: 1 reference(s)