Life1^DBA/2
QTL Variant Detail

Summary

• QTL variant: Life1^DBA/2
• Name: lifespan variability, 1; DBA/2
• MGI ID: MGI:5692139
• QTL: Life1 Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: DBA/2

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:47919

Authors localized a quantitative trait locus (QTL) termed Life1, correlated with the variability in the rate at which genetically identical members of a population die. Twenty-two individual BXD (C57BL/6J x DBA/2) strains were analyzed in a genome-wide search for linkage with previously mapped traits and markers. Analysis revealed strong linkage to one genomic interval - a near - centromeric segment of mouse Chromosome 11. Markers most closely linked to Life1 are D11Byu1 and Glns-ps1.

References

• Original: J:47919 de Haan G, et al., A putative gene causes variability in lifespan among genotypically identical mice [letter] [see comments]. Nat Genet. 1998 Jun;19(2):114-6
• All: 1 reference(s)