Neocv1^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Neocv1^DBA/2J
• Name: neocortex volume 1; DBA/2J
• MGI ID: MGI:5692216
• QTL: Neocv1 Location: unknown Genetic Position: Chr6, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:153478

54 BXD RI lines (C57BL/6J x DBA/2J) were used to map brain neocortical volume to mouse Chromosome 6 and 11. C57BL/6J has a larger neocortical volume then does DBA/2J. The chromosome 6 QTL ( Neocv1 )maps between 88 and 92 Mbs with a LRS of 13.3 and a LOD of 2.9. The chromosome 11 QTL ( Neocv2 )maps between 35 and 40 Mbs with a LRS of 12.7 and a LOD of 2.6. Various candidate genes are listed in Table 1 and Table 2 of the reference.

References

• Original: J:153478 Gaglani SM, et al., The genetic control of neocortex volume and covariation with neocortical gene expression in mice. BMC Neurosci. 2009;10:44
• All: 1 reference(s)