Pircd1^129S1/svImJ
QTL Variant Detail

Summary

• QTL variant: Pircd1^129S1/svImJ
• Name: proteinuria induced renal collagen deposition 1; 129S1/svImJ
• MGI ID: MGI:5692247
• QTL: Pircd1 Location: unknown Genetic Position: Chr2, Syntenic

Variant origin

• Strain of Specimen: 129S1/SvImJ

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:152877

A QTL for proteinuria induced renal collagen deposition (Pircd1) known as type 1 collagen deposition in the kidney was mapped to mouse Chromosome 2. 120 progeny from a backcross of (129S1/svImJ X C57BL/6J)F1 mice with C57BL/6J were used for mapping.Strain analysis indicated that 129S1/svImJ had a higher deposition then did C57BL/6J mice. Pircd1 mapped with D2Mit224 (LRS=11.1, LOD=2.41) in mouse Chromosome 2. The authors indicated that Pircd1 was a suggestive QTL.

References

• Original: J:152877 Kato N, et al., Mapping quantitative trait loci for proteinuria-induced renal collagen deposition. Kidney Int. 2008 May;73(9):1017-23
• All: 1 reference(s)