Sst2^C3H/HeJ
QTL Variant Detail

Summary

• QTL variant: Sst2^C3H/HeJ
• Name: susceptibility to tuberculosis 2; C3H/HeJ
• MGI ID: MGI:5692306
• QTL: Sst2 Location: Chr7:18728794-119485380 bp Genetic Position: Chr7, Syntenic

Variant origin

• Strain of Specimen: C3H/HeJ

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:155722

A genome wide scan in Sst1 resistant (C3H.B6 X C57BL/6J)F2 mice was performed for the purpose of discovering additional loci affecting susceptibility to tuberculosis in mice. Four mouse chromosome regions were identified. Provided here is the chromosome and marker followed by the range , LOD score and resistant allele in parenthesis: Chromosome 7 , Sst2 (D7Mit76 - D7Mit66, LOD = 4.8, C57BL/6J ), Chromosome 12: Sst3 (D12Mit76 - Tel, LOD = 6.6, C3H/HeJ), Chromosome 15 , Sst4 (D15Mit209 - Tel, LOD = 4.6, C57BL/6J ), Chromosome 17 , Sst5 (D17Mit133 - D17Mit87, LOD = 5.5, C57BL/6J ).

References

• Original: J:155722 Yan BS, et al., Genetic architecture of tuberculosis resistance in a mouse model of infection. Genes Immun. 2006 Apr;7(3):201-10
• All: 1 reference(s)