Tons1^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Tons1^DBA/2J
• Name: tongue size 1; DBA/2J
• MGI ID: MGI:5692438
• QTL: Tons1 Location: unknown Genetic Position: Chr5, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:153405

Forty-Three BXD RI strains were use to map QTL for tongue length, fungiform papillae number and total papillae area in mice. A total of 118 mice were analyzed. C57BL/6J mice had a longer tongue then did DBA/2J. C57BL/6J mice contain more fungiform papillae then DBA/2J by 15-20%. Significant QTL for tongue length occurred in chromosomes 5 (Tons1) and 7 (tons2) with suggestive QTL in chromosomes 11 and 17. The Chromsome 5 QTL was associated (LRS 20.608) with 4 SNPs, rs4225252, rs3719870, rs3711269 and rs13478309 spanning between 66 and 68 Mbs. The chromosome 7 QTL for tongue length included many significant SNPs between 114.5 Mbs and 126 Mbp the most significant LRS of 35.135 occurred at SNP rs13479477. A significant QTL (Tpapa1) for total papillae area was observed on Chromosome 19 with a LRS of 18.3 at 55 Mbp and a suggestive QTL was observed in chromosome 10. A suggestive QTL for fungiform papillae number occurred in mouse Chromosome 2 .

References

• Original: J:153405 Reiner DJ, et al., Genetic analysis of tongue size and taste papillae number and size in recombinant inbred strains of mice. Chem Senses. 2008 Oct;33(8):693-707
• All: 1 reference(s)