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Tg(Krt19-cre/ERT2)#Tcw
Transgene Detail
Summary
Symbol: Tg(Krt19-cre/ERT2)#Tcw
Name: transgene insertion, Timothy C Wang
MGI ID: MGI:5692448
Synonyms: Krt19-CreERT2
Transgene: Tg(Krt19-cre/ERT2)#Tcw  Location: unknown  
Alliance: Tg(Krt19-cre/ERT2)#Tcw page
Transgene
origin
Strain of Origin:  CBA x C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Krt19-cre/ERT2)#Tcw expression driven by 1 gene
 
Mutation detailsBAC RP-23-24N13 was used to generate containing an inducible cre recombinase gene (cre/ERT2) inserted at the translation initiation site to achieve expression in the colon and intestine. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:224765)
Recombinase
activity
Activity:
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Driver: Krt19 (mouse)
Summary of all recombinase alleles driven by Krt19.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:224765 Asfaha S, et al., Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. Cell Stem Cell. 2015 Jun 4;16(6):627-38
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory