Mrpl33^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Mrpl33^{tm1b(KOMP)Wtsi}
• Name: mitochondrial ribosomal protein L33; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5692771
• Gene: Mrpl33 Location: Chr5:31771295-31779988 bp, + strand Genetic Position: Chr5, 17.27 cM, cytoband B1
• Alliance: Mrpl33^{tm1b(KOMP)Wtsi} page
• IMPC: Mrpl33 gene page

Mutation origin

• Mutant Cell Line: EPD0761_5_A09
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Mrpl33^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrpl33 Mutation: 115 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 3 reference(s)