Lrrk1tm1b(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Lrrk1tm1b(KOMP)Wtsi |
Name: |
leucine-rich repeat kinase 1; targeted mutation 1b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5692778 |
Gene: |
Lrrk1 Location: Chr7:65908493-66038089 bp, - strand Genetic Position: Chr7, 35.57 cM
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Alliance: |
Lrrk1tm1b(KOMP)Wtsi page
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IMPC: |
Lrrk1 gene page |
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Mutant Cell Line: |
EPD0073_6_C01 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204739
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Parent Cell Line: |
JM8.F6 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: Cre-mediated excision of the parental Lrrk1tm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:204739)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lrrk1 Mutation: |
78 strains or lines available
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Original: |
J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023; |
All: |
6 reference(s) |
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