Cctq2^SJL/J
QTL Variant Detail

Summary

• QTL variant: Cctq2^SJL/J
• Name: central corneal thickness QTL 2; SJL/J
• MGI ID: MGI:5693530
• QTL: Cctq2 Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: SJL/J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:163199

A genome wide scan using 92 (KS X SJL) F2 mice proved informative to identify CCtq1 on mouse Chromosome 7 with a max LOD score -2.87 at 115 Mb with a interval extending from 65 to 139 Mb. CCtq1 was further characterized by a max LOD score of 3.28 at 105 Mb with a peak at D7Mit321

In addition 84 (KS X NZB)F2 mice were utilized to confirm the existence of the chromosome 7 locus.

F2 mice also identified one suggestive interaction between loci on mouse Chromosome 11 (Cctq2, 21.3 Mb) and another suggestive interacting locus on mouse chromosome 17 (Cctq3, 92.7 Mb).

References

• Original: J:163199 Lively GD, et al., Quantitative trait loci associated with murine central corneal thickness. Physiol Genomics. 2010 Jul 7;42(2):281-6
• All: 1 reference(s)