Tcam1^tm1Zuk
Targeted Allele Detail

Summary

• Symbol: Tcam1^tm1Zuk
• Name: testicular cell adhesion molecule 1; targeted mutation 1, Martin M Matzuk
• MGI ID: MGI:5693866
• Gene: Tcam1 Location: Chr11:106167498-106179571 bp, + strand Genetic Position: Chr11, 68.89 cM
• Alliance: Tcam1^tm1Zuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223210
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced exon 2. Immunofluorescence confirmed the absence of protein expression. (J:223210)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcam1 Mutation: 34 strains or lines available

References

• Original: J:223210 Nalam RL, et al., Testicular cell adhesion molecule 1 (TCAM1) is not essential for fertility. Mol Cell Endocrinol. 2010 Feb 5;315(1-2):246-53
• All: 1 reference(s)