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Gria2tm1.1Bvis
Targeted Allele Detail
Summary
Symbol: Gria2tm1.1Bvis
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 1.1, B Vissel
MGI ID: MGI:5693873
Synonyms: fGluR2
Gene: Gria2  Location: Chr3:80588757-80710142 bp, - strand  Genetic Position: Chr3, 35.5 cM
Alliance: Gria2tm1.1Bvis page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223717
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 11. A floxed neomycin resistance cassette was inserted downstream of exon 11. Cre-mediated recombination removed the selection cassette and left exon 11 floxed. (J:223717)
Generation of the Gria2tm1.1Bvis allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gria2 Mutation:  79 strains or lines available
References
Original:  J:223717 Wiltgen BJ, et al., A role for calcium-permeable AMPA receptors in synaptic plasticity and learning. PLoS One. 2010;5(9)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory