Hycc1^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Hycc1^tm1Vlcg
• Name: hyccin PI4KA lipid kinase complex subunit 1; targeted mutation 1, Velocigene
• MGI ID: MGI:5693960
• Gene: Hycc1 Location: Chr5:24120274-24235688 bp, - strand Genetic Position: Chr5, 10.53 cM, cytoband A3
• Alliance: Hycc1^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224206
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ gene and floxed neomycin resistance cassette replaced exons 2 and 3. (J:224206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hycc1 Mutation: 30 strains or lines available

References

• Original: J:224206 Gazzerro E, et al., Hyccin, the molecule mutated in the leukodystrophy hypomyelination and congenital cataract (HCC), is a neuronal protein. PLoS One. 2012;7(3):e32180
• All: 2 reference(s)