Dpp4^{tm1b(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dpp4^{tm1b(EUCOMM)Wtsi}
• Name: dipeptidylpeptidase 4; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5694187
• Gene: Dpp4 Location: Chr2:62160417-62242575 bp, - strand Genetic Position: Chr2, 35.85 cM, cytoband C2-D
• Alliance: Dpp4^{tm1b(EUCOMM)Wtsi} page
• IMPC: Dpp4 gene page

Mutation origin

• Mutant Cell Line: EPD0233_1_E10
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Dpp4^{tm1e(EUCOMM)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpp4 Mutation: 73 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 3 reference(s)