Kcnt2^tm1.1Clin
Targeted Allele Detail

Summary

• Symbol: Kcnt2^tm1.1Clin
• Name: potassium channel, subfamily T, member 2; targeted mutation 1.1, Christopher J Lingle
• MGI ID: MGI:5694651
• Synonyms: Slick floxed
• Gene: Kcnt2 Location: Chr1:140173896-140539805 bp, + strand Genetic Position: Chr1, 61.62 cM
• Alliance: Kcnt2^tm1.1Clin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: B6/BLU (ES Cell)
• Strain of Origin: C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 22 and a second loxP site downstream of exon22, followed by an FRT-flanked neomycin resistance (neo) cassette which includes a third loxP site. FLP-mediated recombination removed the FRT-flanked neo cassette leaving exon 22 floxed. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnt2 Mutation: 111 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)