Gsdma3^Mhdaclp1
Chemically induced Allele Detail

Summary

• Symbol: Gsdma3^Mhdaclp1
• Name: gasdermin A3; Martin Hrabe de Angelis clinical phenotype 1
• MGI ID: MGI:5694663
• Synonyms: Gsdma3^I359N
• Gene: Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
• Alliance: Gsdma3^Mhdaclp1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation that results in the amino acid substitution of asparagine for isoleucine at position 359 (I359N). (J:220424)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsdma3 Mutation: 26 strains or lines available

References

• Original: J:220424 Kumar S, et al., Gsdma3(I359N) is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis. J Dermatol Sci. 2012 Sep;67(3):190-2
• All: 2 reference(s)