Nlrc4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nlrc4^m1Btlr
• Name: NLR family, CARD domain containing 4; mutation 1, Bruce Beutler
• MGI ID: MGI:5695007
• Synonyms: inwood
• Gene: Nlrc4 Location: Chr17:74733254-74766140 bp, - strand Genetic Position: Chr17, 45.64 cM
• Alliance: Nlrc4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transversion at base pair 74,445,630 (v38) on chromosome 17, or base pair 13,514 in the GenBank genomic region NC_000083. The mutation corresponds to residue 1,973 in the mRNA sequence NM_001033367 within exon 4 of 9 total exons. The mutation results in an isoleucine (I) to threonine (T) substitution at position 586 (I586T). (J:225933)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrc4 Mutation: 69 strains or lines available

References

• Original: J:225933 Shi H, et al., Mutagenetix entry for inwood. MGI Direct Data Submission. 2015
• All: 1 reference(s)