Mlkl^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mlkl^m1Btlr
• Name: mixed lineage kinase domain-like; mutation 1, Bruce Beutler
• MGI ID: MGI:5695009
• Synonyms: necro
• Gene: Mlkl Location: Chr8:112038429-112064809 bp, - strand Genetic Position: Chr8, 57.98 cM, cytoband D3
• Alliance: Mlkl^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 111,312,100 (v38) on chromosome 8, or base pair 26,350 in the GenBank genomic region NC_000074. The mutation is within intron 10, 22 base pairs away from exon 11 (out of 11 total exons). The effect of the necro mutation on the mRNA sequence and protein expression is unknown. (J:225934)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlkl Mutation: 32 strains or lines available

References

• Original: J:225934 Wang Y, et al., Mutagenetix entry for necro. MGI Direct Data Submission. 2015
• All: 1 reference(s)